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Animal models for human cancer : = d...

Martic-Kehl, Marianne I.

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Animal models for human cancer : = discovery and development of novel therapeutics /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Animal models for human cancer :/ edited by Marianne I. Martic-Kehl and P. August Schubiger.
Reminder of title:	discovery and development of novel therapeutics /
other author:	Martic-Kehl, Marianne I.
Published:	Weinheim :Wiley-VCH Verlag GmbH & Co. KGaA, : 2016.,
Description:	xx, 251 p. :ill. (chiefly col.) ;25 cm.C
Subject:	Carcinogenesis - Animal models. -
ISBN:	9783527339976

Animal models for human cancer : = discovery and development of novel therapeutics /
Animal models for human cancer :discovery and development of novel therapeutics /edited by Marianne I. Martic-Kehl and P. August Schubiger. - Weinheim :Wiley-VCH Verlag GmbH & Co. KGaA,2016. - xx, 251 p. :ill. (chiefly col.) ;25 cm.C - Methods and principles in medicinal chemistry ;v. 69t use of animals in translational research -- . - Methods and principles in medicinal chemistry ;v. 69..

Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results. Following ashort historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the handling and housing of animals. It then goes on to describe the animal models available for different cancer types, from natural cancer models in mice and dogs to humanized animals. An evaluation of previously unpublished long-term data from the Swiss canine and feline cancer registry is also included. The final part of the book reviews the lessons learned over the last decade on how to interpret data from animalstudies for improving human therapy and gives recommendations forfuture drug development.

ISBN: 9783527339976US145.20Subjects--Topical Terms:

3197716
Carcinogenesis
--Animal models.

LC Class. No.: RC268.5 / .A55 2016

Dewey Class. No.: 616.0273

Animal models for human cancer : = discovery and development of novel therapeutics /
LDR:02359nam a2200277 a 4500 001 2050887
003 OCoLC
005 20170522052801.0
008 170407s2016 gw a b 001 0 eng d
020 $a 9783527339976 $q (hbk.) : $c US145.20
020 $a 3527339973 $q (hbk.)
020 $a 9783527695898 $q (ePub)
020 $a 3527695982 $q (ePub)
020 $a 9783527695911 $q (ePDF)
020 $a 3527695915 $q (ePDF)
020 $a 9783527695904 $q (Mobi)
020 $a 3527695907 $q (Mobi)
020 $a 9783527695881 $q (oBook)
020 $a 3527695885 $q (oBook)
040 $a NLM $b eng
050 # 4 $a RC268.5 $b .A55 2016
082 0 4 $a 616.0273 $2 23
245 1 0 $a Animal models for human cancer : $b discovery and development of novel therapeutics / $c edited by Marianne I. Martic-Kehl and P. August Schubiger.
260 # $a Weinheim : $b Wiley-VCH Verlag GmbH & Co. KGaA, $c 2016.
300 $a xx, 251 p. : $b ill. (chiefly col.) ; $c 25 cm.C
490 1 $a Methods and principles in medicinal chemistry ; $v v. 69t use of animals in translational research -- $t Study design -- $t Improving external validity of experimental animal data -- $t How to end selective reporting in animal research -- $t A comprehensive overview of mouseModels in oncology -- $t Mouse models of advanced spontaneous metastasis for experimental therapeutics -- $t Spontaneous animal tumor models -- $t Dog models of naturally Occurring cancer -- $t Improving preclinical cancer models : lessons from human and Canine Clinical trials of metronomic chemotherapy.
520 # $a Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results. Following ashort historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the handling and housing of animals. It then goes on to describe the animal models available for different cancer types, from natural cancer models in mice and dogs to humanized animals. An evaluation of previously unpublished long-term data from the Swiss canine and feline cancer registry is also included. The final part of the book reviews the lessons learned over the last decade on how to interpret data from animalstudies for improving human therapy and gives recommendations forfuture drug development.
650 # 0 $a Carcinogenesis $x Animal models. $3 3197716
650 1 2 $a Disease Models, Animal. $3 770901
650 1 2 $a Neoplasms, Experimental. $3 3197717
650 2 2 $a Animal Experimentation $x ethics. $3 3197718
650 2 2 $a Drug Discovery. $3 1359836
700 1 # $a Martic-Kehl, Marianne I. $3 3197713
700 1 # $a Schubiger, P. A. $3 3197714
830 0 $a Methods and principles in medicinal chemistry ; $v v. 69. $3 3197715