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An introduction to statistical genet...

Mills, Melinda,

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An introduction to statistical genetic data analysis /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	An introduction to statistical genetic data analysis // Melinda C. Mills, Nicola Barban, and Felix C. Tropf.
作者:	Mills, Melinda,
其他作者:	Barban, Nicola,
出版者:	Cambridge, Massachusetts :The MIT Press, : c2020.,
面頁冊數:	xvi, 415 p. :ill., maps ;23 cm.
內容註:	Introduction : Fundamental Concepts and the Human Genome -- A Statistical Primer for Genetic Data Analysis -- A Primer in Human Evolution -- Genome-Wide Association Studies (GWAS) -- Introduction to Polygenic Scores and Genetic Architecture -- Gene-Environment Interplay -- Genetic data and analytical challenges -- Working with genetic data Part I : Data management, descriptive statistics and quality control -- Working with genetic data Part II : Association analysis, population stratification, and genetic relatedness -- An applied guide to creating and validating polygenic scores -- Polygenic Score and Gene-Environment Interaction (GxE) Applications -- Applying genome-wide association results -- Mendelian Randomization and instrumental variables -- Ethical Issues in Genomics Research -- Conclusions and Future Directions.
標題:	Genetics - Statistical methods. -
ISBN:	9780262538381

An introduction to statistical genetic data analysis /
Mills, Melinda,

An introduction to statistical genetic data analysis /Melinda C. Mills, Nicola Barban, and Felix C. Tropf. - Cambridge, Massachusetts :The MIT Press,c2020. - xvi, 415 p. :ill., maps ;23 cm.

Includes bibliographical references and index.

Introduction : Fundamental Concepts and the Human Genome -- A Statistical Primer for Genetic Data Analysis -- A Primer in Human Evolution -- Genome-Wide Association Studies (GWAS) -- Introduction to Polygenic Scores and Genetic Architecture -- Gene-Environment Interplay -- Genetic data and analytical challenges -- Working with genetic data Part I : Data management, descriptive statistics and quality control -- Working with genetic data Part II : Association analysis, population stratification, and genetic relatedness -- An applied guide to creating and validating polygenic scores -- Polygenic Score and Gene-Environment Interaction (GxE) Applications -- Applying genome-wide association results -- Mendelian Randomization and instrumental variables -- Ethical Issues in Genomics Research -- Conclusions and Future Directions.

ISBN: 9780262538381GBP38

LCCN: 2019022949Subjects--Topical Terms:

731073
Genetics
--Statistical methods.

LC Class. No.: QH438.4.S73 / M55 2020

Dewey Class. No.: 572.8/60727

National Library of Medicine Call No.: QU 460

An introduction to statistical genetic data analysis /
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245 1 3 $a An introduction to statistical genetic data analysis / $c Melinda C. Mills, Nicola Barban, and Felix C. Tropf.
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300 $a xvi, 415 p. : $b ill., maps ; $c 23 cm.
504 $a Includes bibliographical references and index.
505 0 # $a Introduction : Fundamental Concepts and the Human Genome -- A Statistical Primer for Genetic Data Analysis -- A Primer in Human Evolution -- Genome-Wide Association Studies (GWAS) -- Introduction to Polygenic Scores and Genetic Architecture -- Gene-Environment Interplay -- Genetic data and analytical challenges -- Working with genetic data Part I : Data management, descriptive statistics and quality control -- Working with genetic data Part II : Association analysis, population stratification, and genetic relatedness -- An applied guide to creating and validating polygenic scores -- Polygenic Score and Gene-Environment Interaction (GxE) Applications -- Applying genome-wide association results -- Mendelian Randomization and instrumental variables -- Ethical Issues in Genomics Research -- Conclusions and Future Directions.
650 # 0 $a Genetics $x Statistical methods. $3 731073
650 # 0 $a Genomics $x Statistical methods. $3 751074
650 # 0 $a Genomics $x Data processing. $3 722506
650 # 0 $a Genomics. $3 600531
650 # 0 $a Mathematical models. $3 522882
700 1 # $a Barban, Nicola, $e author. $3 3743784
700 1 # $a Tropf, Felix C., $d 1984- $e author. $3 3743785